U.S.-Developed Vaccine 'Could Eliminate' Breast Cancer

Fox News- U.S. scientists developed a vaccine that could prevent breast cancer and save the lives of millions of women, Sky News reported Monday.

The treatment was tested on mice and showed "overwhelmingly favorable results.”

Dr. Vincent Tuohy, who led the research at the Cleveland Clinic in Ohio, said there was evidence in the initial tests that the vaccine could prevent cancers from forming and stop the growth of existing tumors.

"If it works in humans the way it works in mice, this will be monumental," he said.

"We could eliminate breast cancer. We believe that this vaccine will someday be used to prevent breast cancer in adult women in the same way that vaccines have prevented many childhood diseases."

Researchers injected the test vaccine into six mice that were specifically bred to be prone to breast cancer. None developed any signs of tumors.

A further six mice bred in the same way were injected with a placebo vaccine and all developed tumors.

The drug makes the immune system attack a particular protein found in most breast cancer cells and in the mammary tissues of breastfeeding women.

If clinical tests of the vaccine on humans are successful, women over 40 could be vaccinated against the disease. At that age, breast cancer risk begins to increase and women are less likely to be breastfeeding.

Scary Alzeimer's Predictions..

I've learned a bit about this disease and the predictions for our baby boomer generation- let's hope they find a preventive cure for this devastating disease.

(CBS) In its "Where America Stands" series, CBS News is looking at a broad spectrum of issues facing this country in the new decade.

One in eight Americans over age 65 will eventually develop Alzheimer's disease.

Starting next year, 10,000 baby boomers will turn 65 years old each day. That means over the next four decades the number of patients could triple - to 16 million.

"There is a big tidal wave, a tsunami tidal wave coming out there," said Adrian Ivinson, founding director, of the Harvard Neurodiscovery Center.

While deaths from other diseases have dropped in the last decade - heart disease down 11.5 percent, and stroke down 18.1 percent - deaths from Alzheimer's are up almost 50 percent.

Shirley Carreas was diagnosed with Alzheimer's eight years ago. "I want to live and recognize my children, and my children's children."

With Alzheimer's, annual Medicare costs triple.

Can America cope - with a growing disease -- for which there's no cure?

Ten years ago, the best seemed yet to come for three generations of one New Orleans family. But Lisa Carbo, now 55, had to move in with her mother, Shirley, when the 78-year-old was diagnosed with advanced Alzheimer's disease.

For five years, Lisa juggled caring for her mother and her job as a nurse. But then a curveball. At age fifty-three, Lisa was diagnosed with a genetic form of Alzheimer's - one that often strikes at a much earlier age.

"It floors me. These women raised me," said Aimee Palmer, Lisa's daughter. Aimee's 31-years-old and doesn't want genetic testing because she could have the gene yet never develop the disease - and if nothing could save her, she'd rather not know.

"You can't live your life thinking I'm going to die or I'm going to lose my mind at any moment," Aimee said.

While caring for Alzheimer's patients is critical, the only solution is to discover what causes this disease.

The leading suspect is a protein called "amyloid" - which can form sticky plaques that short-circuit communication between nerve cells and destroy brain tissue. As hundreds of trilions of connections begin to wither, so does memory. Another possible cause? A protein called "tau," which forms "tangles" that damage nerve cells."

Lisa is taking an experimental new drug - one that blocks amyloid formation. It's one of fifty drugs being tested in over a hundred clinical trials nationwide.

"I'd like to get some of my function back and possibly go back to work," Lisa said.

"We have a ton of evidence amyloid buildup happens years before someone forgets where they parked their car," said Dr. Dennis Selkoe, Professor of Neurology at the Harvard Medical School.

"If we can shut down amyloid buildup very early, we think we can protect from Alzheimer's," said Dr. Selkoe.

Dr. Selkoe is a leading proponent of this theory and is invested in a company testing anti-amyloid treatments.

Researchers are looking at another possible amyloid blocker - exercise.

"This could decrease their chance of getting Alzheimer's," LaPook asked.

"We hope that's the case," Dr. Selkoe replied.

"We desperately hope the anti-amyloid drugs work, and if they don't we're going to be in a fix," said Dr. Ivinson. "So, we better get started on the next generation."

At Harvard's drug discovery lab, robots can now test hundreds of thousands of chemicals in a matter of weeks - what used to take humans a year.

"You're going to have to tackle this disease from a number of directions, just as we tackle heart disease from a number of directions," Dr. Ivinson said.

As in heart disease, experts believe Alzheimer's needs to be treated early - before symptoms begin.

Woman's Cancer Genome Decoded ?

Talk about personalized medicine: For the first time, scientists have mapped all the genes in a single person's cancer, allowing them to uncover eight new genes that could lead to better ways to treat the disease.
Researchers used malignant blood cells from a 50-something woman who died of acute myeloid leukemia, a cancer of blood-forming cells in the bone marrow, according to a paper in today's Nature. Doctors mapped all the genes in her tumor cells, the compared them — side by side — with the genes in a normal cell from her skin.
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